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APFEL Extruder – Precision Granulation with Cutting-Edge Extrusion Technology!
Experience the next level of pharmaceutical granulation with APFEL’s Extruder, engineered for superior efficiency, precision, and scalability. Designed for wet and melt granulation processes, our extruders provide exceptional control over granule size, shape, and density, ensuring optimal flow properties for tablet compression and capsule filling.
Extruder Types & Configurations
Single-Screw Extruder
The high-shear single-screw design is optimized for efficient wet granulation, offering precise granule size control with reduced fines formation. Available in:
✔ AXS-35 – R&D Scale (Capacity: 5 – 15 kg/hr)
✔ AXS-60 – Pilot Scale (Capacity: 15 – 80 kg/hr)
✔ AXS-70 – Production Scale (Capacity: 80 – 200 kg/hr)
Like the Twin-Screw models, Single-Screw extruders also come in specialized configurations:
🔹 Cone Extruder – Ensures uniform material flow with low-shear processing, preventing granule degradation.
Unrivaled Technical Advantages
✔ Optimized Die Plate Design – Customizable die plates allow precise granule shaping and uniform density, ensuring seamless downstream processing.
✔ Advanced Granule Size Control – Adjustable cutter speeds and mesh configurations deliver precise granule distribution, enhancing tablet compression efficiency.
✔ High-Precision Gear & Temperature Control – Closed-loop temperature monitoring prevents thermal degradation, ensuring stability for heat-sensitive APIs.
✔ Seamless Scalability – Smooth transition from R&D to full-scale production with consistent batch quality.
✔ Energy-Efficient Cooling System – Features air, water, or chiller-based cooling options to maintain optimal extrusion temperatures.
Twin-Screw Extruder
The high-torque twin-screw system ensures continuous mixing, kneading, and granulation, delivering homogeneous dispersion of active ingredients. Available in the following sizes:
✔ AXT-35 – Ideal for R&D applications (Capacity: 5 – 20 kg/hr)
✔ AXT-60 – Designed for pilot-scale production (Capacity: 20 – 100 kg/hr)
✔ AXT-70 – Optimized for high-volume manufacturing (Capacity: 100 – 250 kg/hr)
Each model is further classified into four distinct extrusion types based on material flow and die plate configuration:
🔹 Cone Extruder – Ensures uniform material flow, ideal for delicate formulations requiring minimal shear stress.
🔹 Radial Extruder – Provides optimized granule formation with uniform particle distribution, enhancing compressibility.
🔹 Axial Extruder – Facilitates high-density granule production with excellent sphericity, improving tablet hardness and dissolution control.
🔹 Dome Extruder – Ensures high-throughput processing with controlled residence time, ideal for heat-sensitive formulations.
APFEL Extruder Models & Processing Capacities
Model | Screw Type | Scale | Capacity (kg/hr) | Extruder Type | Cooling System |
AXT-35 | Twin-Screw | R&D Scale | 5 – 20 | Cone, Radial, Axial, Dome | Water-Cooled |
AXT-60 | Twin-Screw | Pilot Scale | 20 – 100 | Cone, Radial, Axial, Dome | Heat-Exchange System |
AXT-70 | Twin-Screw | Production Scale | 100 – 250 | Cone, Radial, Axial, Dome | High-Capacity Chiller |
AXS-35 | Single-Screw | R&D Scale | 5 – 15 | Cone | Water-Cooled |
AXS-60 | Single-Screw | Pilot Scale | 15 – 80 | Cone | Closed-Loop Cooling |
AXS-70 | Single-Screw | Production Scale | 80 – 200 | Cone | High-Efficiency Air Cooling |